Benzodiazepine Guide 2023: Uses, Risks, Withdrawal, and Addiction Recovery

Benzodiazepines, often referred to as "benzos," have become a topic of increasing interest and concern in recent years. These medications, while beneficial for many, come with a set of challenges and potential risks. In this article, we'll delve into the world of benzodiazepines, covering:

  • Benefits of Benzodiazepines: How they provide relief for conditions like anxiety and insomnia.

  • Potential Dangers: The risks associated with prolonged use and overdose.

  • Withdrawal Challenges: The physical and psychological symptoms that can arise when discontinuing use.

  • Tapering Strategy: The importance of a safe and medically supervised approach to reducing dosage.

  • Broader Implications: The societal impact of benzodiazepine use.

  • Support and Resources: Guidance for those who may be struggling with addiction or seeking more information.

Benzodiazepines Explained

Benzodiazepines are medications that doctors prescribe for conditions like anxiety, insomnia, and certain seizure disorders. They're known for their fast-acting relief, which can be invaluable for someone experiencing a severe anxiety attack or a sleepless night. However, as with many medications, there's a dangerous side to consider.

Potential Risks of Benzodiazepine

  • Physical Dependence: Over time, the body can become reliant on benzos. This isn't merely a psychological attachment; the body physiologically requires the drug to maintain normal function. If someone tries to stop or reduce their dose abruptly, they can experience severe physical withdrawal symptoms, including loss of control of emotions (laughing fits, crying fits, fits of rage), seizure, and death.

  • Cognitive Effects: Chronic use of benzos can lead to cognitive issues. This might manifest as memory lapses, difficulty concentrating, or feeling "out of it." Long time use can also lead to seizures. Benzos should not be used longer than 2-4 weeks, which includes the taper off time. Use longer than this seriously increases the risks of dependence and addiction.

  • Increased Accident Risk: The sedative properties of benzos can slow reaction times and impair judgment. This raises the risk of accidents, especially falls in older adults.

  • Overdose Potential: Benzos on their own can be dangerous in high doses, but the risk multiplies if combined with other substances, especially alcohol or opioids. This combination can lead to respiratory depression, a potentially fatal condition where breathing becomes dangerously slow. In addition, as tolerance builds, higher doses of benzos are required, which puts long time users at a high risk. It is estimated that around 17% of overdose deaths are due to benzos misuse.

A Thoughtful Approach to Benzodiazepine Use

If you're considering benzos, it's crucial to see the bigger picture. While they offer important, rapid relief, there are long-term considerations. Engage in a thorough discussion with your doctor, focusing not just on the immediate benefits but also on a long-term strategy and tapering off plan. Make sure your doctor will be available for follow up support.

Questions to consider include: How long will you be on them? What's the plan for tapering off the medication? Are there other treatments or therapies that might be beneficial? What kind of follow up does the doctor provide? Regular check-ins with a healthcare professional can help ensure you're using the medication safely and effectively.

Benzodiazepines: Short-Term Relief vs. Long-Term Implications

Short-Term Benefits

Benzodiazepines shine in their ability to provide immediate relief. For someone in the throes of trauma, a panic attack or lying awake due to crippling anxiety, these medications can feel like a lifeline. Their rapid action can help:

  • Calm Severe Anxiety: Within minutes to hours, the overwhelming sensations of anxiety can be reduced, allowing individuals to function more normally.

  • Promote Sleep: For those battling insomnia, benzos can help initiate and maintain sleep, providing much-needed rest.

Long-Term Concerns

In general, benzo use is not recommended for longer than 2-4 weeks including tapering period. Remember, you cannot quit “cold turkey”. The longer someone uses benzodiazepines, the more complex the picture becomes:

  • Tolerance: As the body gets used to the presence of the drug, higher doses might be needed to achieve the same effect. This not only increases the risk of side effects but also heightens the potential for overdose.

  • Physical Dependence: With prolonged use, the body doesn't just "like" the drug; it expects it. Discontinuing or even just reducing the dose can lead to a host of withdrawal symptoms, from heightened anxiety to physical symptoms like tremors or seizures, even death.

  • Cognitive Impact: Over time, regular use can affect cognitive function. This can range from occasional forgetfulness to more pronounced memory issues or slowed thinking.

  • Mental Health Repercussions: Some users report a paradoxical increase in anxiety or the emergence of depressive symptoms with long-term use.

Why Do People Use Them Long-Term?

Given the risks, why do some people end up using benzodiazepines
long-term?

  • Immediate Relief: The rapid and effective relief provided by benzos can make them seem indispensable, especially during challenging times.

  • Dependence: Over time, the body can become physically reliant on benzodiazepines. This isn't a matter of willpower or choice; it's a physiological response. Discontinuing the medication can lead to withdrawal symptoms, which can be both physically and emotionally challenging.

  • Fear of Withdrawal: Once the body is dependent on the drug, the mere thought of withdrawal can be daunting. The potential for severe symptoms can make discontinuation seem impossible, even with proper support.

  • Lack of Information: Not everyone is fully informed about the long-term risks associated with benzodiazepines. They might start the medication with the intention of short-term use, but without a clear exit strategy, short-term can easily become long-term, which can lead to addiction.

  • Access to Alternatives: Not everyone has access to or information about alternative treatments. Therapies like Cognitive Behavioral Therapy (CBT) can be effective for conditions like anxiety, but barriers like cost, availability, or even stigma can limit access.

Navigating the Benzodiazepine Journey

If you or a loved one is using or considering benzodiazepines, it's essential to be proactive:

  • Open Dialogue: Maintain an open line of communication with your healthcare provider. Discuss your concerns, ask about the long-term plan, and explore alternatives. Have a support person, friend or family, who you can check in with to help minimize the risk of addiction.

  • Stay Informed: Knowledge is power. Understand the potential risks and benefits of benzodiazepines. This will empower you to make informed decisions about your health.

  • Seek Support: Whether it's through therapy, support groups, or trusted loved ones, having a support system can make a significant difference.

In conclusion, benzodiazepines have their place in the medical world, but like all powerful tools, they must be used with caution and respect. By staying informed and proactive, individuals can navigate the complexities of benzodiazepine use and prioritize their health and well-being. 

Understanding Withdrawal

Stopping benzodiazepines, especially after prolonged use, isn't as simple as just deciding not to take a pill. The body's dependence on the drug can make discontinuation a challenging process:

  • Physical Symptoms: These can manifest as headaches, muscle pain, tremors, and even seizures.

  • Psychological Repercussions: Heightened anxiety, panic attacks, depression, and insomnia can return with a vengeance. For some, these symptoms can be even more intense than before starting the medication.

  • Duration Matters: The length and severity of withdrawal can vary based on the specific benzodiazepine and the duration of use. Short-acting benzos might lead to quicker onset of withdrawal symptoms, while long-acting ones might result in more prolonged and gradual symptoms. 

  • PAWS: Post-Acute Withdrawal Syndrome with Benzodiazepines

PAWS is a set of persistent withdrawal symptoms that can occur after discontinuation of benzodiazepines, as well as other substances. Unlike the acute withdrawal symptoms that appear shortly after discontinuation and subside within a few weeks, PAWS can last for months or even years.

Symptoms of PAWS:

  • Psychological Symptoms: These can include chronic anxiety, mood swings, depression, irritability, and cognitive difficulties such as memory problems and difficulty concentrating.

  • Physical Symptoms: Fatigue, sleep disturbances (either insomnia or hypersomnia), muscle tension, and chronic pain are common.

  • Sensory Symptoms: Some people report heightened sensitivities, like increased sensitivity to stress, light, sound, and touch. Others might experience perceptual distortions, where things might seem unreal or more distant than they are.

Duration and Intensity:

The symptoms of PAWS can fluctuate in intensity. There might be periods where symptoms are minimal or absent, followed by flare-ups where they become more pronounced. This waxing and waning can be unpredictable, making it challenging for individuals to anticipate and manage.

While the exact duration of PAWS varies among individuals, symptoms can persist for months to years after discontinuing benzodiazepines. Some studies suggest that a small subset of individuals might experience symptoms for several years, although they generally decrease in intensity over time.

What's Happening in the Body and Mind:

The exact mechanisms behind PAWS are not fully understood, but several theories exist:

  • Neuroadaptation: Chronic benzodiazepine use affects the brain's neurotransmitter systems, especially the GABA (gamma-aminobutyric acid) system. When the drug is discontinued, it takes time for the brain to readjust and return to its baseline state. This prolonged adjustment period might be responsible for the persistent symptoms of PAWS.

  • Brain Structure Changes: Some research suggests that prolonged benzodiazepine use might lead to changes in areas of the brain associated with cognition and emotion. These changes could contribute to the long-lasting symptoms seen in PAWS.

  • Stress Response: Chronic benzodiazepine use can alter the body's stress response system. Discontinuation might lead to an overactive stress response, contributing to symptoms like anxiety and heightened sensitivity to stressors.

Managing PAWS:

Managing PAWS can be challenging due to its prolonged and fluctuating nature. 

However, several strategies can help:

  • Medical Supervision: Regular check-ins with a healthcare provider can help monitor symptoms and provide guidance on managing them.

  • Supportive Therapies: Cognitive-behavioral therapy, counseling, and support groups can offer emotional support and coping strategies.

  • Lifestyle Adjustments: Stress-reducing practices like meditation, deep breathing exercises, and regular physical activity can help manage symptoms. Do what brings you joy.

  • Medication: In some cases, other medications might be prescribed to manage specific symptoms of PAWS.

In conclusion, while PAWS can be a challenging and prolonged aspect of benzodiazepine discontinuation, understanding its nature and seeking appropriate support can help individuals navigate this phase of recovery.

Tapering: A Safer Exit Strategy

Given the challenges of withdrawal, a gradual tapering process is recommended:

  • Individualized Plans: Tapering isn't a one-size-fits-all process. It needs to be tailored to the individual, considering factors like the specific benzodiazepine, the dose, and the duration of use.

  • Medical Supervision: This journey should never be undertaken alone. Regular check-ins with a healthcare provider are essential to monitor symptoms and adjust the tapering plan as needed.

  • Support Systems: Beyond medical supervision, having a support system in place can make a world of difference. This could be in the form of therapy, support groups, or simply loved ones who understand the challenges.

A Call for Informed Decisions

Benzodiazepines, for all their benefits, come with a set of challenges that cannot be ignored. Whether you're a patient, a loved one, or a healthcare provider, the key lies in making informed decisions. Understand the risks, explore alternatives, and always prioritize health and well-being. In the world of benzodiazepines, knowledge and caution are the best allies.

A Call to Action for Those Struggling with Addiction

If you're reading this, it's possible you're seeking information about benzos addiction, either for yourself or someone you care about. Recognizing the need for information is a significant first step, and we commend you for taking it.

Immediate Steps to Consider

  • Detox Plan: It's crucial to understand that detoxing from benzodiazepines or any other substance should be done under medical supervision. Depending on the severity of your addiction, a specialized detox center might be necessary. This ensures safety, as withdrawal from certain substances can be life-threatening.

  • Insurance Coverage: Both private insurance and government programs like Medicare and Medicaid often, if not always, cover basic detox and treatment services. It's worth checking with your provider or seeking guidance on what's available to you. They hear about it every day, they are used to these calls.

  • Seek Immediate Support: Addiction can be isolating, but you're not alone in this. Crisis helplines are available 24/7 to provide guidance, support, and resources. They can advise you on immediate steps to take and connect you with local resources. SAMHSA’s National Helpline

Remember, seeking help is a sign of strength, not weakness. Every journey begins with a single step.

God, grant me the serenity to accept the things I cannot change, The courage to change the things I can, And the wisdom to know the difference.

Previous
Previous

Exploring the Benefits of CBD

Next
Next

Israel's Leading Role in Cannabis Research